SEMA4C |
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Identifiers |
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Aliases | SEMA4C, M-SEMA-F, SEMACL1, SEMAF, SEMAI, semaphorin 4C |
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External IDs | OMIM: 604462; MGI: 109252; HomoloGene: 23047; GeneCards: SEMA4C; OMA:SEMA4C - orthologs |
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Gene location (Human) |
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![Chromosome 2 (human)](//upload.wikimedia.org/wikipedia/commons/thumb/a/aa/Ideogram_human_chromosome_2.svg/300px-Ideogram_human_chromosome_2.svg.png) | Chr. | Chromosome 2 (human)[1] |
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| Band | 2q11.2 | Start | 96,859,718 bp[1] |
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End | 96,870,757 bp[1] |
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Gene location (Mouse) |
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![Chromosome 1 (mouse)](//upload.wikimedia.org/wikipedia/commons/thumb/f/fb/Ideogram_house_mouse_chromosome_1.svg/260px-Ideogram_house_mouse_chromosome_1.svg.png) | Chr. | Chromosome 1 (mouse)[2] |
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| Band | 1|1 B | Start | 36,587,720 bp[2] |
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End | 36,597,430 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - olfactory bulb
- trigeminal ganglion
- spinal ganglia
- cerebellar vermis
- tibial nerve
- inferior ganglion of vagus nerve
- sural nerve
- inferior olivary nucleus
- endothelial cell
- pericardium
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| Top expressed in | - sciatic nerve
- trigeminal ganglion
- aortic valve
- Rostral migratory stream
- otolith organ
- utricle
- ascending aorta
- ganglionic eminence
- tail of embryo
- decidua
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| More reference expression data |
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BioGPS | ![](//upload.wikimedia.org/wikipedia/commons/thumb/2/28/PBB_GE_SEMA4C_219039_at_fs.png/250px-PBB_GE_SEMA4C_219039_at_fs.png)
![](//upload.wikimedia.org/wikipedia/commons/thumb/3/33/PBB_GE_SEMA4C_46665_at_fs.png/250px-PBB_GE_SEMA4C_46665_at_fs.png) | More reference expression data |
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Gene ontology |
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Molecular function | - protein binding
- neuropilin binding
- semaphorin receptor binding
- chemorepellent activity
| Cellular component | - integral component of membrane
- postsynaptic membrane
- postsynaptic density
- plasma membrane
- synapse
- synaptic vesicle membrane
- cell junction
- cytoplasmic vesicle
- extracellular space
- membrane
- integral component of plasma membrane
| Biological process | - cell differentiation
- cell migration in hindbrain
- cerebellum development
- nervous system development
- multicellular organism development
- muscle cell differentiation
- neural tube closure
- positive regulation of stress-activated MAPK cascade
- semaphorin-plexin signaling pathway
- negative chemotaxis
- neural crest cell migration
- positive regulation of cell migration
- negative regulation of axon extension involved in axon guidance
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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NM_001126047 NM_001304329 NM_001304330 |
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RefSeq (protein) | | |
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NP_001119519 NP_001291258 NP_001291259 |
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Location (UCSC) | Chr 2: 96.86 – 96.87 Mb | Chr 1: 36.59 – 36.6 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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